Ginkgo Biloba Extract

1 General Description:

Specification Standards :

(1)Routine
Total Ginkgo flavone glycosides > 24%
Quercatin: kaemperol 0.8--1.5
Total terpene lactones > 6%

(2) CP2005
Total Ginkgo flavone glycosides > 24%
Quercatin: kaemperol 0.8--1.5
Total terpene lactones > 6%
Ginkgolic acid < 10ppm

(3) EGB761
Total Ginkgo flavone glycosides > 24%
Quercatin: kaemperol 0.8--1.5
Total terpene lactones > 6%
Ginkgolic acid < 5ppm

(4) Minimal acid
Total Ginkgo flavone glycosides > 24%
Quercatin: kaemperol 0.8--1.5
Total terpene lactones > 6%
Ginkgolic acid < 1ppm

(5) Europe Standards
Total Ginkgo flavone glycosides 22-27%
Total terpene lactones 5-7%
G.A+G.B+G.C 2.8-3.4%
B.B 2.6-3.2%
Ginkgolic acid <5ppm;<1ppm

The quality specification of ginkgo biloba extract in CP2005:

Preparation: Withdraw under a reflux condenser of ethanol ,adsorb with macroporous resin, spray to dry, comminute.

Character: Yellowish brown to brownish powder, mildly bitter flavour

Test: Moisture<5.0%

Residue on ignition<0.8%

Heavy metal is not more than twenty millionths, namely less than 20ppm

The peak area ratio of flavonoid glycoside, namely Quercatin: kaemperol should be 0.8--1.5

Total ginkgo acid should be not more than ten millionths, namely 10ppm

Assay: High performance liquid chromatography

Total Ginkgo flavone glycosides >24%

The content of total ginkgo flavone glycosides is the sum of the content of quercatin, kaemperol and isorhamnetin (Quercatin: kaemperol 0.8-1.5. If it surpasses 1.5, it should be suspected to add quercatin.)

Total terpene lactones > 6%

The content of total terpene lactones is the sum of the content of bilobalide, ginkgolide A, B and C.

Function:

Promoting blood circulation, removing blood stasis and obstruction in the channels. It is indicated in the prevention and treatment of obstruction of Qi in chest and stroke induced by blood stasis with symptoms including chest pain, palpitations, stiff tongue, dysphasia or aphasia, hemiparalysis, coronary disease, angina pectoris, Cardiac infarction, cerebral coronary thrombembolia,etc.

it is widely used as the additive in health care products, foods, beverages and cosmetics etc.

2.Manufacturing Data:

Botanical Name : Ginkgo biloba L.

Part of plant used : leaves ;

Method of Manufacturing : maceration , reflux ;

Solvent for Extraction : Ethanol / water

Carrier / Excipient : none ;

Ratio of Botanical to Native Extract: 50:1

3.Quality Data :

Description: Yellowish brown to brownish powder;mildly bitter flavour ;

Particle Size : 80 mesh

Loss on Drying: Not more than 5%

Heavy Metals <20ppm

4.Microbiological Inspection :

Total Plate Count <1000cfu/g

Total Mold Count <100cfu/g

E. Coli  Negative

Live Mite Negative

5.Manufacture:

tel:+86-574-66105155, fax +86-574-87450359

mingqianwang@hotmail.com, mingqianw@yahoo.com.cn

www.herbstars.com

银杏叶提取物 Ginkgo Biloba Extract                          

1 General Description/概述：

Specification Standards /规格标准：

我公司可供应以下规格：

（1）常规产品（未处理银杏酸）
银杏黄酮 ≥24%
槲皮素与山奈酚峰比0.8- -1.5之间
银杏总内酯≥6%

（2）中国药典2005版标准
银杏黄酮 ≥24%
槲皮素与山奈酚峰比0.8- -1.5之间
银杏总内酯≥6%
银杏酸 ＜10ppm

(3) 低酸银杏叶提取物 EGB761
银杏黄酮 ≥24%
槲皮素与山奈酚峰比0.8- -1.5之间
银杏总内酯≥6%
银杏酸 ＜5ppm

（4）超低酸银杏叶提取物
银杏黄酮 ≥24%
槲皮素与山奈酚峰比0.8- -1.5之间
银杏总内酯≥6%
银杏酸 ＜1ppm

5、欧洲标准银杏叶提取物
银杏黄酮22-27%，
银杏总内酯5-7%
G.A+G.B+G.C 2.8-3.4%
B.B 2.6-3.2%
银杏酸<5ppm;<1ppm

2005版中国药典银杏叶提取物质量标准：

制法：乙醇回流提取，大孔树脂吸附，喷干，粉碎。

性状：浅棕黄色至棕褐******末；味微苦。

检查：水分小于5.0%；

      炽灼残渣小于0.8%；

      重金属不得过百万分之二十，即20ppm以下。

      黄酮苷元峰面积比，槲皮素与山奈素的峰面积比应为0.8至1.5。

      总银杏酸不得过百万分之十，即10ppm。

含量测定：高效液相色谱法。

总黄酮醇苷不得少于24.0%；

总黄酮醇苷含量=槲皮素含量+山奈素含量+异鼠李素含量。（槲皮素与山奈素的峰面积比应为0.8至1.5之间。如果超过1.5，则应怀疑被人为添加了槲皮素。）

萜类内脂总量不得少于6.0%；

萜类内脂总量=白果内脂+银杏内脂A+银杏内脂B+银杏内脂C。

Function /功效：

活血化瘀、通脉舒络、益气健脑。主要用于脑部，周边血流循环障碍。

适应症：

1.急慢性脑机能不全，注意力不集中，记忆力衰退，老年痴呆，及脑血管硬化症状，中风后遗症。

2.耳部之血流及神经障碍，如耳鸣、眩晕和突聋。

3.眼部之血流及神经障碍，如糖尿病视网膜病变和老年黄斑部退化。

4.末稍循环障碍，如周边动脉阻塞症，间歇破行症和手、脚的冰冷麻痹。

2.Manufacturing Data /生产数据：

Botanical Name / 植物名：银杏 Ginkgo biloba L.

Part of plant used /使用部位：叶

Method of Manufacturing /生产方法：maceration reflux

Solvent for Extraction /提取溶剂：Ethanol / water

Carrier / Excipient /辅料/ 赋型剂：无

Ratio of Botanical to Native Extract /原材料与提取物比率：50：1

3.Quality Data /质量数据：

Description/性状：浅棕黄色至棕褐******末；味微苦。

Particle Size /粉末细度： 80 mesh

Loss on Drying /干燥失重：Not more than 5%

Heavy Metals /重金属：≤20ppm

4.Microbiological Inspection / 微生物：

Total Plate Count ＜1000cfu/g

Total Mold Count ＜100cfu/g

E. Coli  Negative

Live Mite Negative

5.Manufacture/生产商:

宁波德康生物 王明谦

tel:+86-574-66105155, fax +86-574-87450359

mingqianwang@hotmail.com

www.herbstars.com